Reduction of cellulite and fat deposits.
Cellulite involves changes in the dermis and subcutaneous tissue caused by the irregular proliferation of fat cells, the so-called adipocytes. Cellulite is associated with lifestyle, diet and the use of different types of pharmaceutics. Nowadays injected PPC is an effective treatment to reduce cellulite and fat deposits but it involves important discomfort and potential side effects. We created is a perfect alternative by creating a transdermal PPC encapsulated in vesicles of approx. 100 nm in diameter, three synergistically acting active ingredients are contained – L-carnitine, caffeine and sodium deoxycholate – which up to now have been used mainly in invasive aesthetic medicine treatments. These substances were selected in such a way as to most effectively reduce fat tissue, at the same time improving skin elasticity and firmness at the site of application, which have been proved in many studies. L-carnitine speeds up the energetic metabolism of fatty acids and acts as a detoxificant for skin cells. Sodium deoxycholate effectively liquefies the cell membranes of fat cells, the so-called adipocytes, allowing the release of the unnecessary products of metabolism (lipolysis). Caffeine stimulates microcirculation, thus strengthening the action of the other active ingredients. Additionally, it speeds up lipolysis, leading to an increase in the blood level of glycerol and free fatty acids.
Studies confirming an increase in the effectiveness of the action of caffeine and L-carnitine contained in the micro capsules. An increase in the permeability, and a longer release of the substances, contained in it. The studies on transdermal PPC confirmed a speed-up of fat hydrolysis in adipocyte cells in total safety.